DDX41 抗体 (AA 230-280)
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北京 101111
Quick Overview for DDX41 抗体 (AA 230-280) (ABIN5689942)
抗原
See all DDX41 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-280
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特异性
- At least two isoforms of DDX41 are known to exist, this antibody will detect both isoforms.
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纯化方法
- DDX41 Antibody is affinity chromatography purified via peptide column.
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免疫原
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DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41.
The immunogen is located within amino acids 230 - 280 of DDX41. -
亚型
- IgG
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应用备注
- DDX41 antibody can be used for detection of DDX41 by Western blot at 1 - 2 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DDX41 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- DDX41 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DDX41 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 41 (DDX41))
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别名
- DDX41
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背景
- DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.
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分子量
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Predicted: 68 kDa
Observed: 70 kDa -
基因ID
- 51428
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NCBI登录号
- NP_057306
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UniProt
- Q9UJV9
抗原
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