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CRH 抗体 (AA 30-80)

This anti-CRH antibody is a 兔 多克隆 antibody detecting CRH in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN5689930
发货至: 中国

Quick Overview for CRH 抗体 (AA 30-80) (ABIN5689930)

抗原

See all CRH 抗体
CRH (Corticotropin Releasing Hormone (CRH))

适用

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宿主

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克隆类型

  • 80
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多克隆

标记

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This CRH antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    AA 30-80

    特异性

    CRH antibody is human specific.

    纯化方法

    CRH antibody is affinity chromatography purified via peptide column.

    免疫原

    CRH antibody was raised against a 16 amino acid peptide near the amino terminus of human CRH.

    The immunogen is located within amino acids 30 - 80 of CRH.

    亚型

    IgG
  • 应用备注

    CRH antibody can be used for detection of CRH by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    CRH antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    CRH antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    CRH (Corticotropin Releasing Hormone (CRH))

    别名

    CRH

    背景

    Corticotropin-releasing hormone (CRH) is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress (1). In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta where it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturitio (2). Marked reduction in this protein has been observed in association with Alzheimer disease (3).

    分子量

    Predicted: 22 kDa

    Observed: 29 kDa

    基因ID

    1392

    NCBI登录号

    NP_000747

    UniProt

    P06850

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
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