CRH 抗体 (AA 30-80)
Our Local Distributor
北京 101111
Quick Overview for CRH 抗体 (AA 30-80) (ABIN5689930)
抗原
See all CRH 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 30-80
-
特异性
- CRH antibody is human specific.
-
纯化方法
- CRH antibody is affinity chromatography purified via peptide column.
-
免疫原
-
CRH antibody was raised against a 16 amino acid peptide near the amino terminus of human CRH.
The immunogen is located within amino acids 30 - 80 of CRH. -
亚型
- IgG
-
-
-
-
应用备注
- CRH antibody can be used for detection of CRH by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- CRH antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- CRH antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- CRH (Corticotropin Releasing Hormone (CRH))
-
别名
- CRH
-
背景
- Corticotropin-releasing hormone (CRH) is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress (1). In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta where it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturitio (2). Marked reduction in this protein has been observed in association with Alzheimer disease (3).
-
分子量
-
Predicted: 22 kDa
Observed: 29 kDa -
基因ID
- 1392
-
NCBI登录号
- NP_000747
-
UniProt
- P06850
-
途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour
抗原
-