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SNRPE 抗体 (AA 330-380)

This anti-SNRPE antibody is a 兔 多克隆 antibody detecting SNRPE in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5689894
发货至: 中国

Quick Overview for SNRPE 抗体 (AA 330-380) (ABIN5689894)

抗原

See all SNRPE 抗体
SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

适用

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人, 小鼠, 大鼠

宿主

  • 82
  • 1

克隆类型

  • 83
多克隆

标记

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This SNRPE antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 330-380

    特异性

    At least two isoforms of B-raf are known to exist, this antibody will detect both isoforms. This antibody will not cross-react with C-raf.

    纯化方法

    B-raf Antibody is affinity chromatography purified via peptide column.

    免疫原

    B-raf antibody was raised against a 19 amino acid peptide near the center of human B-raf.

    The immunogen is located within amino acids 330 - 380 of B-raf.

    亚型

    IgG
  • 应用备注

    B-raf antibody can be used for detection of B-raf by Western blot at 1 and 2 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    B-raf Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    B-raf antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

    别名

    B-raf

    背景

    B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

    分子量

    Predicted: 84

    Observed: 99, multiple post-translational modifications, commonly observed at 95-100kDa

    基因ID

    673

    UniProt

    P15056

    途径

    Ribonucleoprotein Complex Subunit Organization, Hepatitis C
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