ATM Interactor 抗体 (AA 200-250)
Quick Overview for ATM Interactor 抗体 (AA 200-250) (ABIN5689887)
抗原
See all ATM Interactor (ATMIN) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 200-250
-
特异性
- ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.
-
纯化方法
- ATMIN antibody is affinity chromatography purified via peptide column.
-
免疫原
-
ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN.
The immunogen is located within amino acids 200 - 250 of ATMIN. -
亚型
- IgG
-
-
anti-ATM Interactor (ATMIN) (AA 160-360) antibody
ATMIN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATM Interactor (ATMIN) (AA 1-667) antibodyATMIN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-ATM Interactor (ATMIN) (AA 160-360) antibodyATMIN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ATM Interactor (ATMIN) antibodyATMIN 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATM Interactor (ATMIN) (AA 576-625) antibodyATMIN 适用: 人, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 2.5 μ,g/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- ATMIN Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- ATM Interactor (ATMIN)
-
别名
- ATMIN
-
背景
- The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).
-
分子量
-
Predicted: 73, 79, 91 kDa
Observed: 72 kDa -
基因ID
- 23300
-
NCBI登录号
- NP_056066
-
UniProt
- O43313
抗原
-
