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Cofilin1/2 (CFL1/2) (pTyr88) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN5689861
发货至: 中国

Quick Overview for Cofilin1/2 (CFL1/2) (pTyr88) 抗体 (ABIN5689861)

抗原

See all Cofilin1/2 (CFL1/2) 抗体
Cofilin1/2 (CFL1/2)

适用

  • 13
  • 11
  • 9
人, 小鼠

宿主

  • 13

克隆类型

  • 13
多克隆

标记

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 5
  • 4
  • 4
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 10
    • 2
    • 1
    pTyr88

    特异性

    This antibody detects endogenous level of cofilin1/cofilin2 only when phosphorylated at tyrosine 88.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

    免疫原

    cofilin1/cofilin2 (phospho-Tyr88) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y (p) -E-T) derived from Human coflin1/cofilin2.
  • 应用备注

    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    Cofilin1/2 (CFL1/2)

    别名

    cofilin1 / cofilin2

    背景

    Controls reversibly actin polymerization and depolymerization in a  pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

    分子量

    19 kDa

    基因ID

    1072, 1073

    NCBI登录号

    NP_005498, NP_068733

    UniProt

    P23528, Q9Y281

    途径

    Tube Formation, CXCR4-mediated Signaling Events
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