Cofilin1/2 (CFL1/2) (pTyr88) 抗体
The 兔 多克隆 anti-Cofilin1/2 antibody is suitable to detect Cofilin1/2 in samples from 人 和 小鼠. It has been validated for IHC 和 WB.
产品编号 ABIN5689861
发货至:
中国
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中国
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北京 101111
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Quick Overview for Cofilin1/2 (CFL1/2) (pTyr88) 抗体 (ABIN5689861)
抗原
See all Cofilin1/2 (CFL1/2) 抗体
Cofilin1/2 (CFL1/2)
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
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抗原表位
- pTyr88
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特异性
- This antibody detects endogenous level of cofilin1/cofilin2 only when phosphorylated at tyrosine 88.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
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免疫原
- cofilin1/cofilin2 (phospho-Tyr88) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 88 (A-T-Y (p) -E-T) derived from Human coflin1/cofilin2.
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应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- Cofilin1/2 (CFL1/2)
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别名
- cofilin1 / cofilin2
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背景
- Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
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分子量
- 19 kDa
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基因ID
- 1072, 1073
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NCBI登录号
- NP_005498, NP_068733
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UniProt
- P23528, Q9Y281
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途径
- Tube Formation, CXCR4-mediated Signaling Events
抗原
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