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SNCA 抗体 (pTyr136)

This anti-SNCA antibody is a 兔多克隆 antibody detecting SNCA in WB 和 IF. Suitable for 人, 小鼠和大鼠.

产品编号 ABIN5689835

发货至: 中国

Quick Overview for SNCA 抗体 (pTyr136) (ABIN5689835)

抗原

See all SNCA 抗体

SNCA (Synuclein, alpha (SNCA))

适用

269
166
153
14
10
10
9
7
7
5
2
2
1
1
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

155
23
19
13
9
8
8
7
7
7
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
2

This SNCA antibody is un-conjugated

应用范围

231
160
119
77
75
51
31
28
27
25
23
18
12
8
7
2
2
2
1
1
1
1

Western Blotting (WB), Immunofluorescence (IF)

Discover our top product SNCA Primary Antibody

抗原表位
55

31

15

15

13

13

10

10

6

6

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr136

特异性

This antibody detects endogenous level ofα,-Synuclein only when phosphorylated at tyrosine 136.

纯化方法

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

免疫原

a-Synuclein (Phospho-Tyr136) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 136 (Q-D-Y (p) -E-P) derived from Human α,-Synuclein.
anti-Synuclein, alpha (SNCA) (pSer129) antibody
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Synuclein, alpha (SNCA) (AA 61-140) antibody
SNCA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (HRP)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal HRP

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (FITC)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal FITC

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Biotin)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PE)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PE

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (APC)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal APC

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PerCP)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP

anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 488)
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488

应用备注

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store antibody at -20°C for up to one year.
抗原

SNCA (Synuclein, alpha (SNCA))

别名

a Synuclein

背景

May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

分子量

18 kDa

基因ID

6622

NCBI登录号

NP_000336

UniProt

P37840

途径

Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity

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