Tumor Protein p73 抗体 (AA 97-101)
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- 抗原 See all Tumor Protein p73 (TP73) 抗体
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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抗原表位
- AA 97-101
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Tumor Protein p73 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous level of total p73 protein.
- 纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 免疫原
- p73 (Ab-99) antibody was raised against a peptide sequence around aa.97~101 (S-P-Y-A-Q) derived from Human P73.
- Top Product
- Discover our top product TP73 Primary Antibody
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- 应用备注
- Western Blot: 1:500~1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store antibody at -20°C for up to one year.
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- 抗原
- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
- 别名
- p73 (TP73 产品)
- 别名
- P73 antibody, Trp73 antibody, TP73 antibody, tp73 antibody, Tp73 antibody, p73 antibody, TAp73 antibody, zp73theta antibody, tumor protein p73 antibody, transformation related protein 73 antibody, TP73 antibody, Tp73 antibody, tp73 antibody, Trp73 antibody
- 背景
- This gene encodes tumor protein p73, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73 and have high sequence similarity to one another, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways involving direct or indirect protein interactions, resulting in regulation of the same target gene promoters or regulation of each other's promoters. The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors. The p73 gene expresses at least 35 mRNA variants due to the use of alternate promoters, alternate translation initiation sites, and multiple splice variations. Theoretically this can account for 29 different p73 isoforms, however, the biological validity and the full-length nature of most variants have not been determined.
- 分子量
- 80 kDa
- 基因ID
- 7161
- NCBI登录号
- NP_001119712
- UniProt
- O15350
- 途径
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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