Synaptophysin 2 抗体 (AA 257-261)
This anti-Synaptophysin 2 antibody is a 兔 多克隆 antibody detecting Synaptophysin 2 in WB. Suitable for 大鼠.
Quick Overview for Synaptophysin 2 抗体 (AA 257-261) (ABIN5689618)
抗原
Synaptophysin 2
适用
大鼠
宿主
兔
克隆类型
多克隆
标记
This Synaptophysin 2 antibody is un-conjugated
应用范围
Western Blotting (WB)
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抗原表位
- AA 257-261
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特异性
- This antibody detects endogenous levels of total synaptophysin 2 protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- synaptophysin 2 antibody was raised against a peptide sequence around aa.257~261 (G-P-T-S-F) derived from Rat synaptophysin 2.
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- Synaptophysin 2
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背景
- Synaptophysin (SYP) is a neuronal synaptic vesicle glycoprotein that is expressed in neuroendocrine cells and neoplasms, and thus can be used as a marker in tumor diagnosis (1). Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore (2). Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases (3). Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex (4).
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分子量
- 37 kDa
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基因ID
- 66030
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NCBI登录号
- NP_076464
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UniProt
- P22831
抗原
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