MBP 抗体 (AA 291-295)
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Quick Overview for MBP 抗体 (AA 291-295) (ABIN5689532)
抗原
See all MBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 291-295
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特异性
- This antibody detects endogenous level of total MBP(myelin basic protein) protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- MBP (myelin basic protein) antibody was raised against a peptide sequence around aa.291~295 (G-G-R-D-S) derived from Human MBP.
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- MBP (Myelin Basic Protein (MBP))
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别名
- Myelin basic protein
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背景
- The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
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分子量
- 14~33 kDa
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基因ID
- 4155
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NCBI登录号
- NP_001020252
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UniProt
- P02686
抗原
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