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MBP 抗体 (AA 291-295)

This anti-MBP antibody is a 兔 多克隆 antibody detecting MBP in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5689532
发货至: 中国

Quick Overview for MBP 抗体 (AA 291-295) (ABIN5689532)

抗原

See all MBP 抗体
MBP (Myelin Basic Protein (MBP))

适用

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人, 小鼠, 大鼠

宿主

  • 88
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  • 10
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  • 1

克隆类型

  • 93
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  • 1
多克隆

标记

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This MBP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    • 1
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 291-295

    特异性

    This antibody detects endogenous level of total MBP(myelin basic protein) protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    MBP (myelin basic protein) antibody was raised against a peptide sequence around aa.291~295 (G-G-R-D-S) derived from Human MBP.
  • 应用备注

    Western Blot: 1:500~1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    MBP (Myelin Basic Protein (MBP))

    别名

    Myelin basic protein

    背景

    The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

    分子量

    14~33 kDa

    基因ID

    4155

    NCBI登录号

    NP_001020252

    UniProt

    P02686
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