×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
CBL 抗体 (AA 698-702)
This anti-CBL antibody is a 兔 多克隆 antibody detecting CBL in WB 和 IHC. Suitable for 人.
Quick Overview for CBL 抗体 (AA 698-702) (ABIN5689531)
抗原
See all CBL 抗体
CBL
(Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
适用
All reactivities for CBL 抗体
人
宿主
All hosts for CBL 抗体
兔
克隆类型
All clonalities for CBL 抗体
多克隆
标记
All conjugates for CBL 抗体
This CBL antibody is un-conjugated
应用范围
All applications for CBL 抗体
Western Blotting (WB), Immunohistochemistry (IHC)
CBL抗体详情
(hide)
抗原表位
All epitopes for CBL 抗体
AA 698-702
特异性
This antibody detects endogenous level of total c-Cbl protein.
纯化方法
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
免疫原
c-Cbl (Ab-700) antibody was raised against a peptide sequence around aa. 698~702 (T-E-Y-M-T) derived from Human c-Cbl.
Alternatives
(show)
使用细节
(hide)
应用备注
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
限制
仅限研究用
贮存及处理
(hide)
状态
Liquid
浓度
1 mg/mL
缓冲液
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store antibody at -20°C for up to one year.
CBL目标详情
(hide)
抗原
CBL
(Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence (CBL))
别名
c Cbl
背景
Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling.
分子量
120 kDa
基因ID
867
NCBI登录号
NP_005179
UniProt
P22681
途径
TCR Signaling , Interferon-gamma Pathway , EGFR Signaling Pathway , EGFR Downregulation , VEGFR1 Specific Signals
Recently viewed
(hide)
You are here:
首页
原发性抗体
anti-CBL 抗体 (AA 698-702) (ABIN5689531)
Chat with us , powered by LiveChat