PDGFRB 抗体 (AA 749-753)
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Quick Overview for PDGFRB 抗体 (AA 749-753) (ABIN5689529)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 749-753
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特异性
- This antibody detects endogenous level of total PDGF Receptor β, protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- PDGF Receptor beta (Ab-751) antibody was raised against a peptide sequence around aa.749~753 (V-D-Y-V-P) derived from Human PDGFRb.
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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别名
- PDGF Receptor beta
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背景
- PDGF Receptor β, encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
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分子量
- 190 kDa
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基因ID
- 5159
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NCBI登录号
- NP_002600
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UniProt
- P09619
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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