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VASP 抗体 (AA 155-159)

This anti-VASP antibody is a 兔 多克隆 antibody detecting VASP in WB 和 IF. Suitable for 人 和 大鼠.
产品编号 ABIN5689501
发货至: 中国

Quick Overview for VASP 抗体 (AA 155-159) (ABIN5689501)

抗原

See all VASP 抗体
VASP (Vasodilator-Stimulated phosphoprotein (VASP))

适用

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  • 1
  • 1
人, 大鼠

宿主

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  • 19
  • 2

克隆类型

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多克隆

标记

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This VASP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 155-159

    特异性

    This antibody detects endogenous level of total VASP protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    VASP (Ab-157) antibody was raised against a peptide sequence around aa.155~159 (R-V-S-N-A) derived from Human VASP.
  • 应用备注

    Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    VASP (Vasodilator-Stimulated phosphoprotein (VASP))

    别名

    VASP

    背景

    Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

    分子量

    50 kDa

    基因ID

    7408

    NCBI登录号

    NP_003361

    UniProt

    P50552

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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