VASP 抗体 (AA 155-159)
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Quick Overview for VASP 抗体 (AA 155-159) (ABIN5689501)
抗原
See all VASP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 155-159
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特异性
- This antibody detects endogenous level of total VASP protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- VASP (Ab-157) antibody was raised against a peptide sequence around aa.155~159 (R-V-S-N-A) derived from Human VASP.
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应用备注
- Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
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别名
- VASP
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背景
- Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
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分子量
- 50 kDa
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基因ID
- 7408
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NCBI登录号
- NP_003361
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UniProt
- P50552
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途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
抗原
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