Doublecortin 抗体 (AA 413-417)
Our Local Distributor
北京 101111
Quick Overview for Doublecortin 抗体 (AA 413-417) (ABIN5689407)
抗原
See all Doublecortin (DCX) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 413-417
-
特异性
- This antibody detects endogenous level of total Doublecortin protein.
-
纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
-
免疫原
- Doublecortin antibody was raised against a peptide sequence around aa.413~417 ( P-T-S-P-G) derived from Human Doublecortin.
-
-
-
-
应用备注
- Western Blot: 1:500~1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store antibody at -20°C for up to one year.
-
-
- Doublecortin (DCX)
-
别名
- Doublecortin
-
背景
- Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
-
分子量
- 40 - 45 kDa
-
基因ID
- 1641
-
NCBI登录号
- NP_000546
-
UniProt
- O43602
抗原
-