SNCA 抗体 (AA 127-135)
Quick Overview for SNCA 抗体 (AA 127-135) (ABIN5689372)
抗原
See all SNCA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 127-135
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特异性
- This antibody detects endogenous level of total Synuclein protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- a-Synuclein (Ab-129) antibody was raised against a peptide sequence around aa.127~131 (M-P-S-E-E) derived from Human α,-Synuclein.
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anti-Synuclein, alpha (SNCA) (pSer129) antibody
SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 61-140) antibodySNCA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibodySNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (HRP)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal HRP
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (FITC)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Biotin)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PE)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PE
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (APC)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal APC
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (PerCP)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal PerCP
anti-Synuclein, alpha (SNCA) (AA 40-140), (pSer129) antibody (Atto 488)SNCA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- SNCA (Synuclein, alpha (SNCA))
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别名
- a Synuclein
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背景
- SncA is a member of the synuclein family of structurally related proteins that are prominently expressed in the central nervous system, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and SncA and Snc-Beta inhibit phospholipase D2 selectively. SncA may serve to integrate presynaptic signaling and membrane trafficking. Aggregated SncA proteins form brain lesions that are hallmarks of neurodegenerative synucleinopathies. Defects in SncA play a role in the pathogenesis of Parkinson disease. SncA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer disease. SncA shares 95 % sequence homology with rat SncA. Rat SncA is specifically expressed in brain and is associated with synaptosomal membranes in neurons
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分子量
- 18 kDa
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基因ID
- 6622
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NCBI登录号
- NP_000336
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UniProt
- P37840
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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