TAZ 抗体 (AA 386-390)
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北京 101111
Quick Overview for TAZ 抗体 (AA 386-390) (ABIN5689355)
抗原
See all TAZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 386-390
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特异性
- This antibody detects endogenous level of total TAZ protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- TAZ antibody was raised against a peptide sequence around aa.386~390 (V-E-S-A-L) derived from Human TAZ.
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anti-Tafazzin (TAZ) (AA 1-262) antibody
TAZ 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Tafazzin (TAZ) (AA 32-60) antibodyTAZ 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tafazzin (TAZ) (AA 1-100) antibodyTAZ 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tafazzin (TAZ) (AA 46-240) antibodyTAZ 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tafazzin (TAZ) (AA 95-262) antibodyTAZ 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tafazzin (TAZ) (AA 154-292) antibodyTAZ 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tafazzin (TAZ) (AA 32-60), (N-Term) antibodyTAZ 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21836 unconjugated
anti-Tafazzin (TAZ) (AA 1-262) antibodyTAZ 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3C10 unconjugated
anti-Tafazzin (TAZ) (AA 174-248) antibodyTAZ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tafazzin (TAZ) (AA 46-239) antibodyTAZ 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western Blot: 1:500~1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- TAZ (Tafazzin (TAZ))
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别名
- TAZ
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背景
- Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.
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分子量
- 49 kDa
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基因ID
- 25937
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NCBI登录号
- NP_001161750
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UniProt
- Q9GZV5
抗原
-
