PK (AA 449-453) 抗体
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Quick Overview for PK (AA 449-453) 抗体 (ABIN5689314)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 449-453
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特异性
- This antibody detects endogenous level of total PKR protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- PKR (Ab-451) antibody was raised against a peptide sequence around aa.449~453 (K-G-T-L-R) derived from Human PKR.
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应用备注
- Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- PK
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背景
- Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
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分子量
- 68 kDa
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基因ID
- 5610
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NCBI登录号
- NP_001129123
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UniProt
- P19525
抗原
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