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HNRNPA1 抗体 (AA 190-194)

This anti-HNRNPA1 antibody is a 兔 多克隆 antibody detecting HNRNPA1 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5689290
发货至: 中国

Quick Overview for HNRNPA1 抗体 (AA 190-194) (ABIN5689290)

抗原

See all HNRNPA1 抗体
HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HNRNPA1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 190-194

    特异性

    This antibody detects endogenous levels of total hnRNP A1 protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    hnRNP A1 (Ab-192) antibody was raised against a peptide sequence around aa.190~194 (S-S-S-Q-R) derived from Human hnRNP A1.
  • 应用备注

    Western Blot: 1:500~1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

    别名

    hnRNP A1

    背景

    Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP A/B family of related RNA binding proteins that bind pre-mRNA and are involved in the processing, metabolism and transport of nuclear pre-mRNA transcripts . hnRNP A1 regulates the alternative splicing of c-Src, c-H-Ras and modifies initiation of translation of the fibroblast growth factor 2 mRNA. hnRNP A1 expression level is elevated in many cancers, knockdown of hnRNP A1 leads to apoptosis in various cancer cells . Although predominantly nuclear, hnRNP A1 is continually transported from the nucleus to the cytoplasm where it disassociates from mRNA and is rapidly re-imported into the nucleus . hnRNP A1 binds to cis-acting repressive sequences (CRS) of HIV-1 to influence HIV-1 production . HIV-1 enhances hnRNP A1 expression and promotes the relocalization of hnRNP A1 to the cytoplasm ,

    分子量

    34, 39 kDa

    基因ID

    3178

    NCBI登录号

    NP_002127

    UniProt

    P09651
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