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HDAC3 抗体 (AA 420-424)

This anti-HDAC3 antibody is a 兔 多克隆 antibody detecting HDAC3 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5689286
发货至: 中国

Quick Overview for HDAC3 抗体 (AA 420-424) (ABIN5689286)

抗原

See all HDAC3 抗体
HDAC3 (Histone Deacetylase 3 (HDAC3))

适用

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人, 小鼠, 大鼠

宿主

  • 97
  • 26
  • 1

克隆类型

  • 95
  • 29
多克隆

标记

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This HDAC3 antibody is un-conjugated

应用范围

  • 97
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  • 26
  • 17
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  • 10
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  • 6
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 18
    • 16
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    • 11
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    • 4
    • 3
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    • 1
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    • 1
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    • 1
    AA 420-424

    特异性

    This antibody detects endogenous level of total HDAC3 protein.

    纯化方法

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    免疫原

    HDAC3 antibody   was raised against a peptide sequence around aa.420~424 (N-D-K-E-S) derived from Human HDAC3.
  • 应用备注

    Western Blot: 1:500~1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store antibody at -20°C for up to one year.
  • 抗原

    HDAC3 (Histone Deacetylase 3 (HDAC3))

    别名

    HDAC3 

    背景

    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1, increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation

    分子量

    49 kDa

    基因ID

    8841

    NCBI登录号

    NP_003874

    UniProt

    O15379

    途径

    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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