ADIPOQ 抗体 (AA 235-239)
Our Local Distributor
北京 101111
Quick Overview for ADIPOQ 抗体 (AA 235-239) (ABIN5689238)
抗原
See all ADIPOQ 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 235-239
-
特异性
- This antibody detects endogenous level of total Adiponectin protein.
-
纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
-
免疫原
- Adiponectin antibody was raised against a peptide sequence around aa.235~239 (T-G-F-L-L) derived from Human Adiponectin.
-
-
-
-
应用备注
- Western Blot: 1:500~1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store antibody at -20°C for up to one year.
-
-
- ADIPOQ (Adiponectin (ADIPOQ))
-
别名
- Adiponectin
-
背景
- Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-κ,-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
-
分子量
- 27 kDa
-
基因ID
- 9370
-
NCBI登录号
- NP_001171271
-
UniProt
- Q15848
抗原
-