FOXO4 抗体 (AA 195-199)
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Quick Overview for FOXO4 抗体 (AA 195-199) (ABIN5689227)
抗原
See all FOXO4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 195-199
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特异性
- This antibody detects endogenous level of total AFX protein.
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纯化方法
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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免疫原
- AFX (Ab-197) antibody was raised against a peptide sequence around aa. 195~199 (A-A-S-M-D) derived from Human AFX.
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应用备注
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store antibody at -20°C for up to one year.
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- FOXO4 (Forkhead Box O4 (FOXO4))
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别名
- AFX
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背景
- Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
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分子量
- 65 kDa
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基因ID
- 4303
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NCBI登录号
- NP_001164402
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UniProt
- P98177
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
抗原
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