IL-11 抗体
Quick Overview for IL-11 抗体 (ABIN5689028)
抗原
See all IL-11 (IL11) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Anti-hIL-11 specific antibody was purified by affinity chromatography employing immobilized hIL-11 matrix.
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免疫原
- Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-11 (human Interleukin-11).
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anti-Interleukin 11 (IL11) (AA 22-199) antibody
IL11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 22-120) antibodyIL11 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 27-61) antibodyIL11 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56890 unconjugated
anti-Interleukin 11 (IL11) antibody (Biotin)IL11 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 11 (IL11) (AA 25-74) antibodyIL11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Interleukin 11 (IL11) (AA 25-199) antibodyIL11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (N-Term) antibodyIL11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neutralization:
To yield one-half maximal inhibition [ND50] of the biological activity of hIL-11 (1.50 ng/mL), a concentration of 0.02 - 0.05 μ,g/mL of this antibody is required.
ELISA:
To detect hIL-11 by direct ELISA (using 100 μ,L/well antibody solution) a concentration of at least 0.5 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hIL-11.
Sandwich:
To detect hIL-11 by sandwich ELISA (using 100 μ,L/well antibody solution) a concentration of 0.5 - 2.0 μ,g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human IL-11 (XP-5164Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hIL-11.
Western Blot:
To detect hIL-11 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ,g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-11 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. -
限制
- 仅限研究用
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状态
- Lyophilized
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储存条件
- -20 °C
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储存方法
- IL-11 antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. Avoid repeated freeze-thaw cycles.
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- IL-11 (IL11) (Interleukin 11 (IL11))
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别名
- IL-11
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背景
- Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.
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基因ID
- 3589
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UniProt
- P20809
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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