Synaptotagmin 抗体 (Ser309)
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北京 101111
Quick Overview for Synaptotagmin 抗体 (Ser309) (ABIN5688918)
抗原
See all Synaptotagmin (SYT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Ser309
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特异性
- Synaptotagmin antibody is specific for Mr 60 - 62k synaptotagmin phosphorylated at Ser309.
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纯化方法
- Affinity Purified
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免疫原
- Synaptotagmin (Ser309) polyclonal antibody was raised against a synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Ser309 of synaptotagmin.
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应用备注
- Applications include Dot Blots (DB) and Western Blots (WB). Suitability for Immunohistochemistry (IHC) has not yet been determined. Human, mouse, and rat have 100 % amino acid sequence identity with the antigen used to raise the antibody. When internally tested under ideal conditions the working dilutions were 1:1000 for DB and WB.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.
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- Synaptotagmin (SYT)
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别名
- Synaptotagmin
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背景
- Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis. Moreover recent studies indicate that the protein also plays a key role in endocytosis. Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission.
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分子量
- 60/62 kDa
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基因ID
- 25716
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UniProt
- P21707
抗原
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