Glycogen Synthase 抗体 (pSer9)
Quick Overview for Glycogen Synthase 抗体 (pSer9) (ABIN5688910)
抗原
See all Glycogen Synthase (GYS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer9
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纯化方法
- Affinity Purified
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser9 of GSK3b.
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应用备注
- The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with human, mouse, chicken, bovine, canine, non-human primate, Zebra fish and Xenopus based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Glycogen synthase antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- Glycogen Synthase (GYS)
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别名
- Glycogen synthase
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背景
- Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that is involved in the regulation of many signaling pathways. To date, 2 isoforms have been identified: GSK3alpha and GSK3beta. Specifically, GSK3beta has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways (Papkoff and Aikawa 1998). It has been suggested that Ser9 phosphorylation underlies the inhibition of GSK3beta by insulin (Sutherland et al., 1993).
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分子量
- 46 kDa
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基因ID
- 84027
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UniProt
- P18266
抗原
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