GABA B Receptor (pSer783) 抗体
适用: 人, 小鼠, 大鼠, 非洲爪蟾, 小鸡, Cow
IHC, WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- GABA B Receptor
- 抗原表位
- pSer783
- 适用
- 人, 小鼠, 大鼠, 非洲爪蟾, 小鸡, Cow
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- 非结合性
-
应用范围
- Immunohistochemistry (IHC), Western Blotting (WB)
- 纯化方法
- Affinity Purified
- 免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser783 of GABAB R2.
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anti-GABA B Receptor antibody
适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-GABA B Receptor (C-Term) antibody适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with mouse, human, non-human primate, chicken, bovine and Xenopus tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
- 储存条件
- -20 °C
- 储存方法
- GABAB Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- 抗原
- GABA B Receptor
- 别名
- GABAB Receptor
- 背景
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. It has recently been demonstrated that AMPK binds directly to GABAB receptors and phosphorylates S783 in the cytoplasmic tail of the R2 subunit and that S783 plays a critical role in enhancing neuronal survival after ischemia as phosphorylation of S783 is evident in many brain regions and is increased dramatically after ischemic injury to the brain (Kuramoto et al., 2007).
- 分子量
- 102 kDa
- 基因ID
- 83633
- UniProt
- O88871
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