STXBP1 抗体 (pSer515)
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Quick Overview for STXBP1 抗体 (pSer515) (ABIN5688903)
抗原
See all STXBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer515
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纯化方法
- Affinity Purified
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免疫原
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser515 of Munc-18.
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应用备注
- The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primates and Xenopus based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Munc-18 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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别名
- Munc-18
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背景
- Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein (Sassa et al., 1996).
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分子量
- 65 kDa
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基因ID
- 81804
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UniProt
- Q62753
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途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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