AQP2 抗体 (pSer261)
Quick Overview for AQP2 抗体 (pSer261) (ABIN5688893)
抗原
See all AQP2 抗体适用
宿主
克隆类型
标记
应用范围
- 
    
- 
                                            
抗原表位
 - pSer261
 - 
                                            
纯化方法
 - Affinity Purified
 - 
                                            
免疫原
 - Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser261 of rat aquaporin 2.
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with canine, bovine, chicken, human, mouse and non-human primate tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Liquid
 - 
                                            
缓冲液
 - 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
 - 
                                            
储存条件
 - -20 °C
 - 
                                            
储存方法
 - Aquaporin 2 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
 
 - 
                                            
 - 
    
- 
                                            : "Immunohistochemical Expression of AQP2 and HSP70 in Broiler Kidney Tissue Treated with Salix tetrasperma Roxb. Extract under Heat Exposure."    in: TheScientificWorldJournal, Vol. 2021, pp. 8711286, (2022)         (PubMed).        
 
 - 
                                            : "Immunohistochemical Expression of AQP2 and HSP70 in Broiler Kidney Tissue Treated with Salix tetrasperma Roxb. Extract under Heat Exposure."    in: TheScientificWorldJournal, Vol. 2021, pp. 8711286, (2022)         (PubMed).        
 - 
    
- AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
 - 
                                            
别名
 - Aquaporin 2
 - 
                                            
背景
 - Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans (Iolascon et al.,2007). A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells (van Balkom et al., 2002). Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking (Hoffert et al., 2007).
 - 
                                            
分子量
 - 29/37 kDa
 - 
                                            
基因ID
 - 25386
 - 
                                            
UniProt
 - P34080
 - 
                                            
途径
 - Response to Water Deprivation
 
抗原
 -