电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

AQP2 抗体 (pSer261)

This anti-AQP2 antibody is a 兔 多克隆 antibody detecting AQP2 in WB 和 IHC. Suitable for 人, 大鼠, 小鼠, Cow, 犬 和 小鸡. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN5688893
发货至: 中国

Quick Overview for AQP2 抗体 (pSer261) (ABIN5688893)

抗原

See all AQP2 抗体
AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

适用

  • 112
  • 95
  • 78
  • 14
  • 14
  • 10
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 大鼠, 小鼠, Cow, 犬, 小鸡

宿主

  • 134
  • 4

克隆类型

  • 134
  • 5
多克隆

标记

  • 53
  • 10
  • 9
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AQP2 antibody is un-conjugated

应用范围

  • 121
  • 43
  • 41
  • 40
  • 34
  • 20
  • 20
  • 18
  • 18
  • 15
  • 12
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 21
    • 19
    • 18
    • 16
    • 15
    • 14
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer261

    纯化方法

    Affinity Purified

    免疫原

    Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser261 of rat aquaporin 2.
  • 应用备注

    The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with canine, bovine, chicken, human, mouse and non-human primate tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    Aquaporin 2 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • Sugito, Etriwati, Akmal, Rahmi, Delima, Muchlisin, Hasan: "Immunohistochemical Expression of AQP2 and HSP70 in Broiler Kidney Tissue Treated with Salix tetrasperma Roxb. Extract under Heat Exposure." in: TheScientificWorldJournal, Vol. 2021, pp. 8711286, (2022) (PubMed).

  • 抗原

    AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

    别名

    Aquaporin 2

    背景

    Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans (Iolascon et al.,2007). A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells (van Balkom et al., 2002). Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking (Hoffert et al., 2007).

    分子量

    29/37 kDa

    基因ID

    25386

    UniProt

    P34080

    途径

    Response to Water Deprivation
You are here:
Chat with us!