GABRA1 抗体 (N-Term)
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Quick Overview for GABRA1 抗体 (N-Term) (ABIN5688881)
抗原
See all GABRA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Affinity Purified
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免疫原
- Fusion protein from N-terminal region of the a3-subunit of rat GABAA receptor.
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anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody
GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibodyGABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 unconjugated
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (HRP)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) HRP
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (HRP)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 HRP
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (FITC)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) FITC
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (FITC)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 FITC
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (Biotin)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) Biotin
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (Biotin)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 Biotin
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 15-34) antibody (PE)GABRA1 适用: 大鼠 WB, ICC, IF, AA 宿主: 小鼠 Monoclonal N151-3 (Formerly S151-3) PE
anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1) (AA 350-385) antibody (PE)GABRA1 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S399-19 PE
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应用备注
- The antibody has been directly tested for reactivity in Western blots with rat and mouse tissue.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- GABAA Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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别名
- GABAA Receptor
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背景
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and sub-stance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified (Olsen and Tobin, 1990, Whiting et al., 1999, Ogris et al., 2004). Injection in oocytes or mammalian cell lines of cRNA coding for alpha- and beta-subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma-subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha-subunits of the receptor (McKernan et al., 2000, Mehta and Ticku, 1998, Ogris et al., 2004, Pöltl et al., 2003).
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分子量
- 51 kDa
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基因ID
- 24947
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UniProt
- P20236
抗原
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