Connexin 抗体 (C-Term)
This anti-Connexin antibody is a 兔 多克隆 antibody detecting Connexin in WB. Suitable for 小鸡, 犬, 人, 小鼠, 大鼠, 绵羊, 非洲爪蟾 和 斑马鱼.
产品编号 ABIN5688865
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Connexin 抗体 (C-Term) (ABIN5688865)
抗原
Connexin
适用
小鸡, 犬, 人, 小鼠, 大鼠, 绵羊, 非洲爪蟾, 斑马鱼
宿主
兔
克隆类型
多克隆
应用范围
Western Blotting (WB)
-
-
抗原表位
- C-Term
-
纯化方法
- Affinity Purified
-
免疫原
- Peptide corresponding to amino acid residues from the C-terminal region of rat connexin43.
-
-
-
应用备注
- The antibody has been directly tested for reactivity in Western blots in rat tissues. It is anticipated that the antibody will also work with chicken, dog, finch, human, mouse, non-human primate, sheep, Xenopus and zebra fish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
-
储存条件
- -20 °C
-
储存方法
- Connexin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
-
-
- Connexin
-
背景
- Gap junctional intercellular communication is thought to play a key role in development and may also be involved in epilepsy (Aronica et al., 2001). Connexin43 forms gap-junctional channels and regulates the permeability of these gap junctions to small organic molecules. Permeability of connexin43 is known to be regulated by phosphorylation at er368 by protein kinase C (Yogo et al., 2002, Bao et al., 2004a). Phosphorylation of Ser368 by PKC induces a conformational change of connexin43 that results in a decrease in gap junction permeability (Bao et al., 2004b).
-
分子量
- 43 kDa
-
基因ID
- 24392
-
UniProt
- P08050
抗原
-
You are here:
