GRM1a / GRM5 抗体 (C-Term)
This 兔 多克隆 anti-GRM1a / GRM5 antibody specifically detects GRM1a / GRM5 in WB 和 IHC. The antibody is reactive with 大鼠 samples.
产品编号 ABIN5688861
发货至:
中国
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Quick Overview for GRM1a / GRM5 抗体 (C-Term) (ABIN5688861)
抗原
GRM1a / GRM5 (GRM5/1a)
(Glutamate Receptor, Metabotropic 5/1a (GRM5/1a))
适用
大鼠
宿主
兔
克隆类型
多克隆
标记
This GRM1a / GRM5 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
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抗原表位
- C-Term
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纯化方法
- Affinity Purified
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免疫原
- mGluR 5/1a polyclonal antibody was raised against a peptide from the C-terminal region of mGluR5 and mGluR1a.
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anti-Glutamate Receptor, Metabotropic 5/1a (GRM5/1a) (C-Term) antibody
GRM5/1a 适用: 大鼠, 人, 小鼠 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 5/1a (GRM5/1a) (C-Term) antibodyGRM5/1a 适用: 大鼠, 人, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Metabotropic Glutamate Receptor 5/1a antibody allows for strong and specific immunolabeling of ~125k mGluR5 and mGluR1a and the ~250k mGluR5 and mGluR1a dimers in Western blots of rat brain at antibody dilution of 1:1000. Immunolabeling blocked by preadsorption of antibody with the C-terminal peptide immunogen. Applications include Dot Blots (DB), Immunohistochemistry (IHC) and Western Blots (WB). Rabbit anti-mGluR 5/1a recognizes both mGluR5 and mGluR1a in rat brain. When internally tested under ideal conditions the working dilutions were 1:500 for IHC and 1:1000 for DB and WB.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- For long term storage -80°C is recommended, but shorter term storage at -20°C is also acceptable as aliquots may be taken without freeze/thawing due to the presence of 50% glycerol. Stable for one year.
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- GRM1a / GRM5 (GRM5/1a) (Glutamate Receptor, Metabotropic 5/1a (GRM5/1a))
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别名
- Metabotropic Glutamate Receptor 5/1a
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背景
- The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase.
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分子量
- 125/250 kDa
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基因ID
- 24418
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UniProt
- P31424
抗原
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