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SLC6A1 抗体 (C-Term)

This anti-SLC6A1 antibody is a 兔 多克隆 antibody detecting SLC6A1 in WB 和 IHC. Suitable for 大鼠 和 小鼠.
产品编号 ABIN5688853
发货至: 中国

Quick Overview for SLC6A1 抗体 (C-Term) (ABIN5688853)

抗原

See all SLC6A1 (GAT1) 抗体
SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

适用

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大鼠, 小鼠

宿主

  • 35
  • 2
  • 1

克隆类型

  • 36
  • 2
多克隆

标记

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This SLC6A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 4
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    C-Term

    纯化方法

    Affinity Purified

    免疫原

    Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.
  • 应用备注

    The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will also react with mouse tissue based on the fact that this species has 100 % homology with the amino acid sequence used as antigen.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    GAT-1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • 抗原

    SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))

    别名

    GAT-1

    背景

    Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).

    分子量

    67 kDa

    基因ID

    79212

    UniProt

    P23978
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