Vinculin 抗体 (AA 50-100)
Our Local Distributor
北京 101111
Quick Overview for Vinculin 抗体 (AA 50-100) (ABIN5688767)
抗原
See all Vinculin (VCL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 50-100
-
特异性
- Vinculin antibody is human, mouse, rat, rabbit and chicken reactive. At least three isoforms of Vinculin are known to exist.
-
纯化方法
- Vinculin antibody is purified via Protein A prification.
-
免疫原
-
Vinculin antibody was raised against a 23 amino acid peptide near the amino terminus of human Vinculin.
The immunogen is located within amino acids 50 - 100 of Vinculin. -
亚型
- IgG
-
-
-
-
应用备注
- Vinculin antibody can be used for detection of Vinculin by Western blot at 0.5 - 1 μ,g/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Vinculin Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Vinculin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- Vinculin (VCL)
-
别名
- Vinculin
-
背景
- Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).
-
分子量
-
Predicted: 117 kDa
Observed: 120 kDa -
基因ID
- 7414
-
NCBI登录号
- NP_003364
-
途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
-