NEFM 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for NEFM 抗体 (C-Term) (ABIN5688746)
抗原
See all NEFM 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- C-Term
-
特异性
- Specific for the ~145k Neurofilament M protein.
-
纯化方法
- Total IgG fraction
-
免疫原
- Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.
-
亚型
- IgG1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存条件
- -20 °C
-
储存方法
- Neurofilament NF-M antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
-
-
- NEFM (Neurofilament Triplet M Protein (NEFM))
-
别名
- Neurofilament NF-M
-
背景
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease.
-
分子量
- 145 kDa
-
基因ID
- 24588
-
UniProt
- P12839
-
途径
- Brown Fat Cell Differentiation
抗原
-