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TUBB3 抗体

This anti-TUBB3 antibody is a 小鼠 单克隆 antibody detecting TUBB3 in WB 和 IHC. Suitable for 哺乳动物.
产品编号 ABIN5688672
发货至: 中国

Quick Overview for TUBB3 抗体 (ABIN5688672)

抗原

See all TUBB3 抗体
TUBB3 (Tubulin, beta 3 (TUBB3))

适用

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哺乳动物

宿主

  • 92
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  • 4
  • 1
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小鼠

克隆类型

  • 93
  • 78
单克隆

标记

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This TUBB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

AA10
  • 特异性

    Specific for the ~55  kDa beta III tubulin protein. This clone is similar to the monoclonal antibody Tuj1.

    纯化方法

    Protein G purified

    免疫原

    Synthetic peptide corresponding to beta III tubulin.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

    储存条件

    -20 °C

    储存方法

    Beta III Tubulin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
  • 抗原

    TUBB3 (Tubulin, beta 3 (TUBB3))

    别名

    Beta III Tubulin

    背景

    Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)

    分子量

    55 kDa

    基因ID

    246118

    UniProt

    Q4QRB4

    途径

    Microtubule Dynamics, M Phase
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