TUBB3 抗体
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北京 101111
Quick Overview for TUBB3 抗体 (ABIN5688672)
抗原
See all TUBB3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Specific for the ~55 kDa beta III tubulin protein. This clone is similar to the monoclonal antibody Tuj1.
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纯化方法
- Protein G purified
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免疫原
- Synthetic peptide corresponding to beta III tubulin.
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Beta III Tubulin antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- TUBB3 (Tubulin, beta 3 (TUBB3))
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别名
- Beta III Tubulin
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背景
- Tubulin is the major constituent of microtubules, existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al., 1990). Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al., 2003)
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分子量
- 55 kDa
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基因ID
- 246118
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UniProt
- Q4QRB4
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途径
- Microtubule Dynamics, M Phase
抗原
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