Retinoid X Receptor 抗体
The 小鼠 单克隆 anti-Retinoid X Receptor antibody is suitable to detect Retinoid X Receptor in samples from 人, 小鼠, 大鼠 和 Cow. It has been validated for WB.
产品编号 ABIN5688670
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Retinoid X Receptor 抗体 (ABIN5688670)
抗原
Retinoid X Receptor
适用
人, 小鼠, 大鼠, Cow
宿主
小鼠
克隆类型
单克隆
应用范围
Western Blotting (WB)
克隆位点
1373
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纯化方法
- Protein G purified
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免疫原
- Hinge peptide from human retinoid X receptor, y-isotype.
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亚型
- IgG1
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应用备注
- The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, mouse, non-human primate and rat tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Retinoid X Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- Retinoid X Receptor
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背景
- Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
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分子量
- 48 kDa
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基因ID
- 6258
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UniProt
- P48443
抗原
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