Retinoic Acid Receptor gamma 抗体 (N-Term)
Quick Overview for Retinoic Acid Receptor gamma 抗体 (N-Term) (ABIN5688662)
抗原
See all Retinoic Acid Receptor gamma (RARG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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纯化方法
- Protein G purified
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免疫原
- Peptide corresponding to amino acids from N-terminal region of human retinoic acid receptor, b-isotype.
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亚型
- IgG1
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应用备注
- The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with canine, guinea pig, mouse and rat tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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储存条件
- -20 °C
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储存方法
- Retinoic Acid Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))
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别名
- Retinoic Acid Receptor
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背景
- Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
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分子量
- 48 kDa
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基因ID
- 5915
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UniProt
- P10826
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size
抗原
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