POR 抗体 (Internal Region)
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北京 101111
Quick Overview for POR 抗体 (Internal Region) (ABIN568710)
抗原
See all POR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-TNPPRTNVLY E
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特异性
- Recognizes Cytochrome P450 Reductase (CYPOR).
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交叉反应 (详细)
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Species reactivity (expected):Dog, Cow, Pig, Rabbit.
Species reactivity (tested):Human, Mouse, Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_000932.3. Genename: POR
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- POR (P450 (Cytochrome) Oxidoreductase (POR))
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别名
- Cytochrome P450 Reductase
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背景
- P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.Synonyms: CPR, CYPOR, NADPH--cytochrome P450 reductase, P450R, POR
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基因ID
- 5447
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NCBI登录号
- NP_000932
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UniProt
- P16435
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, SARS-CoV-2 Protein Interactome
抗原
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