S1PR2 抗体 (Internal Region)
(1 reference)Our Local Distributor
北京 101111
Quick Overview for S1PR2 抗体 (Internal Region) (ABIN568703)
抗原
See all S1PR2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
序列
- C-NYTKETLETQ
-
特异性
- Recognizes EDG-5 / S1P2.
-
交叉反应 （详细）
-
Species reactivity (expected):Dog.
Species reactivity (tested):Human, Mouse, Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
-
免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_004221.3. Genename: S1PR2
-
-
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (AA 293-353) antibody
S1PR2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (C-Term) antibodyS1PR2 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (AA 39-73) antibodyS1PR2 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB53162 unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (Internal Region) antibodyVerified S1PR2 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (Internal Region) antibodyS1PR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (AA 272-298), (C-Term) antibodyS1PR2 适用: 人 WB 宿主: 兔 Polyclonal RB40507 unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) antibodyS1PR2 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (AA 272-298) antibodyS1PR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 2 (S1PR2) (2nd Cytoplasmic Loop), (AA 129-146) antibodyS1PR2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- Tris saline, pH 7.3, 0.02 % Sodium Azide, 0.5 % BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
-
: "Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11-dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome." in: Anesthesiology, Vol. 129, Issue 2, pp. 311-320, (2019) (PubMed).
-
-
- S1PR2 (Sphingosine-1-Phosphate Receptor 2 (S1PR2))
-
别名
- EDG-5 / S1P2
-
背景
- The EDG (endothelial differentiation gene) family of G protein-coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high-affinity. EDG-6 is a low-affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain. EDG-5 has wide tissue distribution, including cardiovascular tissue and brain. Expressed in lymphoid and hematopoietic tissues and in lung, EDG-6 signals through Gi/o proteins, which activate growth related pathways.Synonyms: AGR16, EDG5, Endothelial differentiation G-protein coupled receptor 5, Gpcr13, H218, LPB2, S1P receptor 2, S1PR2, Sphingosine 1-phosphate receptor 2
-
基因ID
- 9294
-
NCBI登录号
- NP_004221
-
UniProt
- O95136
-
途径
- Synaptic Membrane
抗原
-
