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CIRBP 抗体 (C-Term)

This 山羊 多克隆 antibody specifically detects CIRBP in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬 和 Cow.
产品编号 ABIN568702
发货至: 中国
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Quick Overview for CIRBP 抗体 (C-Term) (ABIN568702)

抗原

See all CIRBP 抗体
CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

适用

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人, 小鼠, 大鼠, 犬, Cow

宿主

  • 60
  • 5
  • 4
山羊

克隆类型

  • 47
  • 22
多克隆

标记

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  • 2
  • 2
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  • 1
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This CIRBP antibody is un-conjugated

应用范围

  • 62
  • 34
  • 22
  • 22
  • 14
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  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    C-Term

    序列

    C-RDSYDSYATH NE

    特异性

    Recognizes CIRBP (aa 161-172).

    交叉反应 (详细)

    Species reactivity (expected):Rat, Canine (Dog), Bovine.
    Species reactivity (tested):Human, Mouse.

    纯化方法

    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the C-Terminus of the protein sequence according to NP_001271.1. Genename: CIRBP
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

    别名

    CIRBP

    背景

    CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature.Synonyms: A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP

    基因ID

    1153

    NCBI登录号

    NP_001271

    UniProt

    Q14011

    途径

    Ribonucleoprotein Complex Subunit Organization
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