ARHGDIA 抗体 (Internal Region)
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Quick Overview for ARHGDIA 抗体 (Internal Region) (ABIN568700)
抗原
See all ARHGDIA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-QLAQIAAENE
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特异性
- Recognizes ARHGDIA.
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交叉反应 (详细)
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Species reactivity (expected):Human, Dog, Cow.
Species reactivity (tested):Mouse, Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequencefrom the internal region of the protein sequence according to NP_004300.1. Genename: ARHGDIA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
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别名
- ARHGDIA / GDIA1
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背景
- Rho GDP-dissociation inhibitor 1, also known ARHGDIA, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. Localized to the cytoplasm, ARHGDIA inhibits the dissociation of GDP from Rho proteins, thereby preventing GTP from binding to and subsequently activating Rho proteins. In humans ARHGDIA can be phosphorylated at Ser 101 by p21-activated kinase, an event that inhibits ARHGDIA activity and may result in positive feedback regulation of certain ARHGDIA target proteins.Synonyms: Rho GDI 1, Rho GDP-dissociation inhibitor 1, Rho-GDI alpha, RhoGDI1
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基因ID
- 396
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NCBI登录号
- NP_004300
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UniProt
- P52565
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途径
- Neurotrophin Signaling Pathway
抗原
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