ITGA2 抗体 (AA 994-1132)
Quick Overview for ITGA2 抗体 (AA 994-1132) (ABIN5684082)
抗原
See all ITGA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 994-1132
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原理
- CD49B Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CD49B (AA: 994-1132) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- ITGA2 (Integrin alpha 2 (ITGA2))
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别名
- CD49B
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背景
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This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
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分子量
- 129.3 kDa
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基因ID
- 3673
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UniProt
- P17301
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途径
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
抗原
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