GUK1 抗体 (Biotin)
Quick Overview for GUK1 抗体 (Biotin) (ABIN568250)
抗原
See all GUK1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Molar Ratio: Biotin/IgG = ~6.6
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纯化方法
- Ammonium Sulphate Precipitation and Ion Exchange Chromatography.
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免疫原
- Guanylate kinase isolated and purified from Porcine brain. Freund’s complete adjuvant is used in the first step of the immunization procedure.
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亚型
- IgG
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anti-Guanylate Kinase 1 (GUK1) antibody
GUK1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Kinase 1 (GUK1) (AA 1-197) antibodyGUK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Kinase 1 (GUK1) (AA 100-197) antibodyGUK1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1H3 unconjugated
anti-Guanylate Kinase 1 (GUK1) (AA 1-197) antibodyGUK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Guanylate Kinase 1 (GUK1) antibodyGUK1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Kinase 1 (GUK1) (AA 1-197) antibodyGUK1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4C3-1A7 unconjugated
anti-Guanylate Kinase 1 (GUK1) antibodyGUK1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Kinase 1 (GUK1) (AA 26-75) antibodyGUK1 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Kinase 1 (GUK1) (AA 71-120) antibodyGUK1 适用: 人, 小鼠, 大鼠, Pig, 马, 斑马鱼, Cow, 犬, 豚鼠, 兔, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Guanylate Kinase 1 (GUK1) (AA 1-197) antibodyGUK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore by adding 1.0 mL sterile distilled water.
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浓度
- 10.0 mg/mL
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缓冲液
- PBS, pH 7.2 without preservatives and foreign proteins.
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储存液
- Without preservative
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
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- GUK1 (Guanylate Kinase 1 (GUK1))
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别名
- Guanylate Kinase / GUK1
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背景
- Guanylate kinase catalyzes the transfer of phosphate from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) or dGMP. This enzyme functions in the recovery of cGMP and is, therefore, thought to regulate the supply of guanine nucleotides to signal transduction pathways. The GUK2 and GUK3 isoforms are determined by separate loci. Brady et al. (1996) cloned human and mouse cDNAs of GUK1. They stated that the guanylate kinases are targets for cancer chemotherapy and are inhibited by the antitumor drug 6-thioguanine. They reported that the human gene codes for a protein of 197 amino acids with a mass of 21.7 kD. They found that the 1-kb message was ubiquitously expressed.Synonyms: GMK, GMP kinase
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基因ID
- 9823
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UniProt
- P31006
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途径
- Nucleotide Phosphorylation, ER-Nucleus Signaling, Ribonucleoside Biosynthetic Process
抗原
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