Ceruloplasmin 抗体 (Biotin)
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北京 101111
Quick Overview for Ceruloplasmin 抗体 (Biotin) (ABIN568139)
抗原
See all Ceruloplasmin (CP) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes Ceruloplasmin from Human serum. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and Enzyme Inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.
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产品特性
- Molar Ratio: Biotin/IgG: ~5.6
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纯化方法
- Ammonium Sulphate Precipitation and Ion Exchange Chromatography
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免疫原
- Ceruloplasmin isolated and purified from Human serum. Freund’s complete adjuvant is used in the first step of the immunization procedure.
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亚型
- IgG
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anti-Ceruloplasmin (Ferroxidase) (CP) (AA 789-1065) antibody
CP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 789-1065) antibodyCP 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 20-258) antibodyCP 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 547-577) antibodyCP 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 121-151) antibodyCP 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 121-151), (N-Term) antibodyCP 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19057 unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 872-1059) antibodyCP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 547-577), (Center) antibodyCP 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19058 unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) antibodyCP 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ceruloplasmin (Ferroxidase) (CP) (AA 872-1059) antibodyCP 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 11# unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore by adding 1.0 mL of sterile distilled water, Prepare working dilutions by adding sterile phosphate buffered saline (PBS, ph 7.2) and preferably use the same day.
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浓度
- 10.0 mg/mL
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缓冲液
- PBS, pH 7.2 without preservatives and foreign proteins
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储存液
- Without preservative
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody lyophilized at 2-8 °C Reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
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- Ceruloplasmin (CP) (Ceruloplasmin (Ferroxidase) (CP))
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别名
- Ceruloplasmin
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背景
- Caeruloplasmin is a copper binding plasma glycoprotein consisting of a single polypeptide chain. It has a molecular weight of 132 kDa and occurs in plasma at a concentration of 150-500 mg/L. Although the physiological functions of Caeruloplasmin are not fully understood it is implicated in a number of possible functions. 95 % of plasma copper is bound to Caeruloplasmin, implying some involvement in copper transport. Caeruloplasmin has been described as both an oxidant and an antioxidant, its exact role or roles in this respect are not clear. Plasma levels of Caeruloplasmin are elevated after inflammation and trauma and it is therefore classified as an acute phase protein. The measurement of Caeruloplasmin in plasma is useful in the diagnosis of Wilson's disease, where levels are greatly reduced. Caeruloplasmin is extremely labile in plasma and rapidly degrades to 115 kDa and 19 kDa fragments. The age of plasma samples should therefore be taken into account when interpreting immunological analysis of caeruloplasmin.Synonyms: CP, Ferroxidase
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基因ID
- 1356
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NCBI登录号
- NP_000087
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UniProt
- P00450
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途径
- Transition Metal Ion Homeostasis
抗原
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