AGE 抗体
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北京 101111
Quick Overview for AGE 抗体 (ABIN5680158)
抗原
See all AGE 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Advanced Glycation End Products (AGE), cross-reactivity BSA-AGE, HSA-AGE <1 %
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交叉反应 (详细)
- Human, rat. Broad reactivity with advanced glycation end products (AGE) in many species.
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产品特性
- This antibody is suitable for the detection of different AGE products in tissues, tissue extracts and body fluids. Long-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE) which are characterized by fluorescence, brown color and inter- and intra-molecular cross-linking. Recent immunological studies using anti-AGE antibodies demonstrated the presence of AGE in (i) human lens, (ii) renal proximal tubules in patients with diabetic nephropathy and chronic renal failure, (iii) atherosclerotic lesions of arterial walls, (iv) ß2-microglobulin of carpal tunnel amyloid fibril deposits in patients with hemodialysis-related amyloidosis and (v) brain tissues of patients with Alzheimer's disease. These results suggested the potential role of AGE in normal aging and age-enhanced disease processes. Advanced Glycation End Products (AGE), cross-reactivity BSA and HSA <1 % .
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纯化方法
- Protein A affinity purified IgG
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免疫原
- Advanced Glycation End Products /BSA/HSA
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亚型
- IgG
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应用备注
- human lens, arteriosclerotic plaques,ELISA, IHC not established,60 min at RT or 18 hr at 2-8 °C,(liquid conc.) ELISA app. 1 μg/mL, (IHC 5-10 μg/mL)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS 0.05 M, pH 7.15, 0.85 % NaCl, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- AGE (Advanced Glycation End Products (AGE))
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别名
- AGE, Advanced Glycation End Products
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物质类
- Chemical
抗原
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