S100B 抗体
Our Local Distributor
北京 101111
Quick Overview for S100B 抗体 (ABIN5680133)
抗原
See all S100B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- S-100 beta, S-100 A (alpha/beta) and S-100 B (beta/beta), not reactive with S-100 A0 (alpha/alpha), Calmodulin, Parvalbumin and other Ca-binding proteins
-
交叉反应 (详细)
- Cattle, human, cat, rabbit, rat, pig
-
产品特性
- The S-100 antibody has frequently been used for the detection of melanoic tumours. In brain tumours and metastases the antibody may be used for differentiation between glia derived tissue and tissues derived from other cell types. S-100 helps in differentiation of Melanoma and Schwannoma from other soft tissue tumours. It is also found in tumours of the salivary glands. S-100 is a homo- or heterodimer filament protein, composed of an alpha and a beta chain. In normal tissues it is found in glia and ependyma of the brain. In the periphery it is found in Schwann Cells, Melanocytes and in Langerhans Cells of the skin. In lymph nodes Interdigitating Cells are labelled. S-100 A0, which is exprimed e.g. by neurons, heart muscle and monocytes, will not be detected by this monoclonal antibody. S-100 ß, S-100 A (alpha/beta) and S-100 B (beta/beta), not reactive with S-100 A0 (alpha/alpha), Calmodulin, Parvalbumin and other Ca-binding proteins.
-
纯化方法
- Antibody solution
-
免疫原
- Purified S-100beta protein from bovine brain
-
亚型
- IgG1
-
-
-
-
应用备注
- Formaldehyde-fixed tissue should be pre-treated with 0.1 % pronase to give best results. Unmasking methods involving microwave or steam cooking are not recommended!,Skin, myelinated nerves,IHC(P),60 min at RT,(liquid conc.) Dilution 1:20 - 1:50 IHC(P)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for at least 100 immunohistochemical tests (100 μL working solution / test)
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
-
- S100B (S100 Calcium Binding Protein B (S100B))
-
别名
- S-100 beta
-
途径
- Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
抗原
-