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CD19 抗体

The 小鼠 单克隆 anti-CD19 antibody (Clone 4G7) (ABIN567993) specifically detects CD19 in FACS 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN567993
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD19 抗体 (ABIN567993)

抗原

See all CD19 抗体
CD19 (CD19 Molecule (CD19))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD19 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

4G7
  • 特异性

    This antibody recognizes CD19 (B4), a 95 kDa type I transmembrane glycoprotein of immunoglobulin superfamily, expressed on B lymphocytes and follicular dendritic cells, it is lost on plasma cells.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Protein-A affinity chromatography

    免疫原

    Human CCL (chronic lymphocytic leukemia) cells

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4 with 15 mM Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD19 (CD19 Molecule (CD19))

    别名

    CD19

    背景

    CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.Synonyms: B-cell marker, B-lymphocyte surface antigen B4, Differentiation antigen CD19, Leu-12

    基因ID

    930

    NCBI登录号

    NP_001761

    UniProt

    P15391

    途径

    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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