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CD3 抗体

CD3 适用: 人 IP, WB 宿主: 仓鼠 Monoclonal HAM25-1352 unconjugated
产品编号 ABIN567797
发货至: 中国
  • 抗原 See all CD3 抗体
    CD3
    适用
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    仓鼠
    克隆类型
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    单克隆
    标记
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    This CD3 antibody is un-conjugated
    应用范围
    • 260
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    Immunoprecipitation (IP), Western Blotting (WB)
    特异性
    This antibody reacts with CD3 epsilon (23 kDa) on Western blotting.
    纯化方法
    Protein-A Agarose Chromatography of hybridoma supernatant.
    免疫原
    Human T3 cells.
    克隆位点
    HAM25-1352
    亚型
    IgG
    Top Product
    Discover our top product CD3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    别名
    CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
    背景
    The antigen receptor of the T lymphocyte consists of two variable T-cell receptor chains (either TCR-apha, TCR-beta or TCR-gamma, TCR-delta) noncovalently linked to four different invariant membrane proteins ((CD3-γ , CD3-δ , CD3-ε , and the CD3-ζ homodimer). The CD3 genes are expressed early in thymocyte development, preceding the rearrangement and expression of the T-cell receptor genes. The CD3 epsilon polypeptide contributes to the cell surface display as well as to the signal transduction properties of the T-cell antigen receptor complex. Intriguingly, the distribution of CD3 epsilon is not restricted to T cells, since activated mouse, human, and avian natural killer (NK) cells do express intracytoplasmic CD3 epsilon polypeptides. CD3 epsilon is also present in the cytoplasm of fetal thymic T/NK bipotential progenitor cells, suggesting that it constitutes a component of the NK differentiation program.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
    基因ID
    916
    NCBI登录号
    NP_000724
    UniProt
    P07766
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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