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CD3 抗体

This anti-CD3 antibody is a 仓鼠 单克隆 antibody detecting CD3 in IP 和 WB. Suitable for 人.
产品编号 ABIN567797
发货至: 中国

Quick Overview for CD3 抗体 (ABIN567797)

抗原

See all CD3 抗体
CD3

适用

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宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD3 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Western Blotting (WB)

克隆位点

HAM25-1352
  • 特异性

    This antibody reacts with CD3 epsilon (23 kDa) on Western blotting.

    纯化方法

    Protein-A Agarose Chromatography of hybridoma supernatant.

    免疫原

    Human T3 cells.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.2 containing 50 % Glycerol without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    CD3

    别名

    CD3

    背景

    The antigen receptor of the T lymphocyte consists of two variable T-cell receptor chains (either TCR-apha, TCR-beta or TCR-gamma, TCR-delta) noncovalently linked to four different invariant membrane proteins ((CD3-γ , CD3-δ , CD3-ε , and the CD3-ζ homodimer). The CD3 genes are expressed early in thymocyte development, preceding the rearrangement and expression of the T-cell receptor genes. The CD3 epsilon polypeptide contributes to the cell surface display as well as to the signal transduction properties of the T-cell antigen receptor complex. Intriguingly, the distribution of CD3 epsilon is not restricted to T cells, since activated mouse, human, and avian natural killer (NK) cells do express intracytoplasmic CD3 epsilon polypeptides. CD3 epsilon is also present in the cytoplasm of fetal thymic T/NK bipotential progenitor cells, suggesting that it constitutes a component of the NK differentiation program.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

    基因ID

    916

    NCBI登录号

    NP_000724

    UniProt

    P07766

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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