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POU2F1 抗体

The 小鼠 单克隆 anti-POU2F1 antibody is suitable to detect POU2F1 in samples from 人 和 小鼠. It has been validated for WB, IP 和 EMSA.
产品编号 ABIN567788
发货至: 中国
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Quick Overview for POU2F1 抗体 (ABIN567788)

抗原

See all POU2F1 抗体
POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

适用

  • 85
  • 35
  • 29
  • 18
  • 17
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 76
  • 9
  • 1
小鼠

克隆类型

  • 74
  • 12
单克隆

标记

  • 54
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This POU2F1 antibody is un-conjugated

应用范围

  • 59
  • 33
  • 28
  • 12
  • 11
  • 9
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Electrophoretic Mobility-Shift Assay (EMSA)

克隆位点

YL15
  • 特异性

    This antibody reacts with Oct-1 (90 kDa) on Western blotting. YL15 recognizes the POU-domain linker region of Human Oct-1.

    纯化方法

    Protein-A Agarose Chromatography of hybridoma supernatant.

    免疫原

    Recombinant full-length Human Oct-1.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.2 containing 50 % Glycerol without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    POU2F1 (POU Domain, Class 2, Transcription Factor 1 (POU2F1))

    别名

    POU2F1 / OCT1

    背景

    Octamer transcrIPPtional factor 1 (Oct-1) is a 90 kDa transcrIPPtion factor that binds to the octamer motif ATTTGCAT. This ubiquitous regulatory element is most conspicuous in B cells, where it is found in every immunoglobulin (Ig) promoter and in most Ig enhancers. In addition, Oct-1 binding also activates the promoters of the genes for some small nuclear RNAs (snRNA) and for histone H2B. Oct-1 protein is expressed in multIPPle tissues although some Oct-1 isoforms appear to be tissue specific and the homologous Oct-2 appears to be restricted in expression to B-cells. At least in B-cells, the Oct proteins bind to DNA together with another protein transcrIPPtion factor, octamer binding factor-1 (OBF-1), to form a ternary complex.Synonyms: NF-A1, OTF1, Oct-1, Octamer-binding protein 1, Octamer-binding transcription factor 1, Otf-1, POU domain class 2 transcription factor 1

    基因ID

    5451

    NCBI登录号

    NP_002688

    UniProt

    P14859
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