EXD2 抗体 (AA 351-621) (FITC)
Quick Overview for EXD2 抗体 (AA 351-621) (FITC) (ABIN5675768)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 351-621
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特异性
- WB shows isoform 2
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human EXD2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
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别名
- EXD2
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背景
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Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2
Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
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基因ID
- 55218
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UniProt
- Q9NVH0
抗原
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