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KPNA6 抗体 (AA 101-200) (HRP)

This anti-KPNA6 antibody is a 兔 多克隆 antibody detecting KPNA6 in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN5675541
发货至: 中国

Quick Overview for KPNA6 抗体 (AA 101-200) (HRP) (ABIN5675541)

抗原

See all KPNA6 抗体
KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

适用

  • 22
  • 20
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 21
  • 1

克隆类型

  • 22
多克隆

标记

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This KPNA6 antibody is conjugated to HRP

应用范围

  • 22
  • 13
  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 101-200

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human KPNA6

    亚型

    IgG
  • 应用备注

    WB 1:300-1000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Gentamicin sulfate

    注意事项

    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

    别名

    KPNA6

    背景

    Synonyms: Importin subunit alpha-7, KPNA6, Karyopherin subunit alpha-6, KPNA6, IPOA7

    Background: Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

    基因ID

    23633

    UniProt

    O60684

    途径

    Protein targeting to Nucleus
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